Mirrored Axis Distortion (MAD) Transform and Visualizations

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Introduction

This webpage contrains vignettes for using the mirrored axis distortion of fold change (MAD-FC) transform for visualizing fold change data. MAD-FC is a transform that combines visualization properties of log and linear plots of fold change. MAD-FC maintains a linear scale for spattially mapping fold change data starting with a linear plot and then distorting negative fold change values to match the scale of positive fold change values. This strategy allows for a more intuitiuve summary of fold change datasets. We argue that MAD-FC plots may be a more useful visualization than log or linear plots for applications that do not require a high dynamic range (instances that require greater than 2.5 orders of magnitude or 8 units in log2 space). For more information, please refer to the publication.

B. A. Corliss, Y. Wang, F. P. Driscoll, H. Shakeri, P. E. Bourne, MAD-FC: A Fold Change Visualization with Readability, Proportionality, and Symmetry (2023), doi:10.48550/arXiv.2303.10829.

Mirrored Axis Distortion of Fold Change Vignettes

1. Volcano and MA Plots
2. Boxplots
3. Errorbar Plots
4. Heatmaps

Bruce Corliss, 10/17/2023